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{{short description|American geneticist}}

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|birth_place = |death_date = |death_place = |residence = |citizenship = |nationality = |ethnicity = |fields = Genetics|workplaces = Carnegie Institution for Science, Howard Hughes Medical Institute|alma_mater = University of Chicago, Massachusetts Institute of Technology|doctoral_advisor =|academic_advisors =|doctoral_students = |notable_students =|known_for = |author_abbrev_bot = |author_abbrev_zoo = |influences = |influenced = Newcomb Cleveland Prize {{smallGenetics Society of America Medal {{small>(1989)}}Edwin Grant Conklin Medal (2003)George W. Beadle Award {{small|(2003)}}ORR-WEAVER > FIRST1 = T., The 2003 George W. Beadle Medal; Gerald M. Rubin and Allan C. Spradling, Genetics, 164, 4, 1248–1249, 2003, 10.1093/genetics/164.4.1248, 15106662, 1462668, Gruber Prize in Genetics {{small|(2008)}}March of Dimes Prize in Developmental Biology {{small|(2018)}} Wiley Prize {{small|(2024)}}}}|religion = |signature = |footnotes = }}Allan C. Spradling is an American scientist and principal investigator at the Carnegie Institution for Science and the Howard Hughes Medical Institute who studies egg development in the model organism, Drosophila melanogaster, a fruit fly.WEB,www.hhmi.org/research/investigators/spradling_bio.html, Howard Hughes Medical Institute Investigators: Allan C. Spradling, Ph.D., 2009-10-25, He is considered a leading researcher in the developmental genetics of the fruit fly egg and has developed a number of techniques in his career that have led to greater understanding of fruit fly genetics including contributions to sequencing its genome. He is also an adjunct professor at Johns Hopkins University and at the Johns Hopkins University School of Medicine.

Education

Spradling obtained an A.B. in physics from the University of Chicago and a Ph.D. in cell biology from the Massachusetts Institute of Technology.

Career

Spradling and fellow American geneticist Gerald M. Rubin are considered pioneers in the field of genetics for their work in the early 1980s with their idea to “attach” a gene to a Drosophila transposon, P elements,JOURNAL, Spradling, A., Rubin, G., 10.1126/science.6289435, Transposition of cloned P elements into Drosophila germ line chromosomes, Science, 218, 4570, 341–347, 1982, 6289435, 1982Sci...218..341S, known to insert itself into fruit fly’s chromosomes.BOOK, Jedicke, Peter, Extreme science: transplanting your head and other feats of the future, 2001, St. Martin’s Griffin, New York, 978-0-312-26819-0, From this research came work from other scientists on transposons as a tool for genetic alterations in organisms.RUBIN > FIRST1 = G. FIRST2 = A., Genetic transformation of Drosophila with transposable element vectors, Science, 218, 4570, 348–353, 1982, 6289436doi = 10.1126/science.6289436, SPRADLING>FIRST1=A.FIRST2=D.LAST3=KAIYEAR=2001JOURNAL=NATUREISSUE=6859BIBCODE=2001NATUR.414...98SPMID=11689954, 2904709, SPRADLING > FIRST1 = A. FIRST2 = D. FIRST3 = A. FIRST4 = E. FIRST5 = T. FIRST6 = N. FIRST7 = S. FIRST8 = G., The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes, Genetics, 153, 1, 135–177, 1999, 10.1093/genetics/153.1.135, 10471706, 1460730, In 2003 Spradling was awarded the Beadle Medal and in 2008 Spradling was awarded the Gruber Prize in Genetics for his work on the Drosophila genome and continues his work in investigating novel technological approaches to genetics, egg development and stem cells. He was elected to the American Philosophical Society in 2016.WEB, APS Member History,search.amphilsoc.org/memhist/search?creator=Allan+Spradling&title=&subject=&subdiv=&mem=&year=&year-max=&dead=&keyword=&smode=advanced, 2021-02-18, search.amphilsoc.org, In 2024 he received the Wiley Prize.Wiley Prize in Biomedical Sciences 2024

References

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