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superagonist
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(File:Efficacy spectrum.png|right|thumb|320px|Efficacy spectrum of receptor ligands.)In the field of pharmacology, a superagonist is a type of agonist that is capable of producing a maximal response greater than the endogenous agonist for the target receptor, and thus has an efficacy of more than 100%.JOURNAL, Carlier PR, Chow ES, Barlow RL, Bloomquist JR, Discovery of non-zwitterionic GABAA receptor full agonists and a superagonist, Bioorg. Med. Chem. Lett., 12, 15, 1985â8, August 2002, 12113824, 10.1016/S0960-894X(02)00299-8, JOURNAL, Tan CM, Wilson MH, MacMillan LB, Kobilka BK, Limbird LE, Heterozygous α2A-adrenergic receptor mice unveil unique therapeutic benefits of partial agonists, Proc. Natl. Acad. Sci. U.S.A., 99, 19, 12471â6, September 2002, 12205290, 129469, 10.1073/pnas.122368499, 2002PNAS...9912471T, free, For example, goserelin is a superagonist of the gonadotropin-releasing hormone receptor.- the content below is remote from Wikipedia
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- "superagonist" does not exist on GetWiki (yet)
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