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{{Short description|Chemical compound}}{{Drugbox| IUPAC_name = 4-[(1S)-2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxyethyl]phenol| image = Denopamine.svg| width = 275| tradename =

international|denopamine}}| pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US =

Japan>JP)

Tablet (pharmacy)>tablets)| bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion =| CAS_number = 71771-90-9| ATC_prefix = none| ATC_suffix = | ATC_supplemental = | PubChem = 71754| ChEMBL = 493682| IUPHAR_ligand = 534| DrugBank = | ChemSpiderID = 64795

correct|FDA}}| UNII = V5F60UPD8P| KEGG = D02614| chemical_formula =

H=23

O=4 | smiles = O(c1ccc(cc1OC)CCNC[C@@H](O)c2ccc(O)cc2)C}}Denopamine (INN) is a cardiotonic drug which acts as a β1 adrenergic receptor agonist.JOURNAL, Ishide T, Denopamine, a selective beta1-receptor agonist and a new coronary vasodilator, Current Medical Research and Opinion, 18, 7, 407–13, 2002, 12487507, 10.1185/030079902125001119, 25048757, It is used in the treatment of anginaJOURNAL, Nakajima D, Negoro N, Nakaboh A, Nakakoji T, Hoshiga M, Nariyama J, Ishihara T, Hanafusa T, 6, Effectiveness of low dose denopamine, a beta1-adrenoceptor agonist, in a patient with vasospastic angina refractory to intensive medical treatment, International Journal of Cardiology, 108, 2, 281–3, April 2006, 15913812, 10.1016/j.ijcard.2005.03.012, and may also have potential uses in the treatment of congestive heart failureJOURNAL, Nishio R, Matsumori A, Shioi T, Wang W, Yamada T, Ono K, Sasayama S, Denopamine, a beta1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-alpha production in the heart, Journal of the American College of Cardiology, 32, 3, 808–15, September 1998, 9741531, 10.1016/S0735-1097(98)00314-3, 2433/181223, free, and for clearing pulmonary oedema.JOURNAL, Sakuma T, Hida M, Nambu Y, Osanai K, Toga H, Takahashi K, Ohya N, Inoue M, Watanabe Y, 6, Beta1-adrenergic agonist is a potent stimulator of alveolar fluid clearance in hyperoxic rat lungs, Japanese Journal of Pharmacology, 85, 2, 161–6, February 2001, 11286398, 10.1254/jjp.85.161, free, It is marketed in Japan under the brand name Kalgut (カルグート) and available as tablets of 5 and 10 mg, and 5% fine granules.WEB, Kalgut (denopamine) Tablets 5, 10 mg; Fine granules 5%. Full Prescribing Information,weblink Mitsubishi Tanabe Pharma Corporation, 6 March 2016, Japanese, References {{reflist|2}}{{Adrenergic agonists}}{{cardiovascular-drug-stub}}